替米沙坦联合左旋氨氯地平对高血压合并2型糖尿病患者糖化血红蛋白水平的影响(1)
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[摘要] 目的 探讨替米沙坦联合左旋氨氯地平对高血压(HT)合并2型糖尿病(T2DM)患者糖化血红蛋白水平(BbA1c)的影响。 方法 将高血压合并2型糖尿病患者178例随机分为观察组与对照组，每组各89例，对照组给予常规治疗加用左旋氨氯地平，观察组则在对照组的基础上加用替米沙坦治疗，治疗12周后，观察并分析两组治疗前后的血压、血脂及糖化血红蛋白的水平。 结果 治疗12周后，观察组总有效率为95.50%，对照组则为77.53%，两组相比较，差异有统计学意义(P < 0.05)；PG、HbA1c及血脂水平均较治疗前下降，差异有统计学意义(P < 0.05)；但组间比较，差异无统计学意义(P > 0.05)；而MAU水平治疗后下降较为明显，且组间比较，差异有统计学意义(P < 0.05)。 结论 替米沙坦联合左旋氨氯地平对高血压合并2型糖尿病患者既能很好地控制血压和降低尿蛋白，又能显著改善患者糖代谢。
[关键词] 高血压；2型糖尿病；替米沙坦；左旋氨氯地平
[中图分类号] R972 [文献标识码] A [文章编号] 1674-4721(2012)02(a)-0071-03
Effect of telmisartan and levamlodipine besylate tablets in resistance on the level of the glycosylated hemoglobin in Type 2 diabetics mellitus patients with hypertension
LI Yong1 CHEN Aihua2 HUANG Jingwen3
1.Department of Cardiology, Chancheng Zhangcha Hospital of Foshan City in Guangdong Province, Foshan 528000, China; 2.Cardiology Department, Southern Medical University Zhujiang Hospital of Guangzhou City in Guangdong Province, Guangzhou 510282, China; 3.Cardiology Department, the People's Hospital of Nanhai District of Foshan City in Guangdong Province, Foshan 528200, China
[Abstract] Objective To discuss the effect of telmisartan and levamlodipine besylate tablets in resistance on the level of the glycosylated hemoglobin in Type 2 diabetics mellitus patients with hypertension. Methods One hundred and seventy-eight cases of Type 2 diabetics mellitus patients with hypertension were chosen and randomly divided into the observation group and the control group, patients in the control group were treated by conventional therapy and added the levamlodipine besylate tablets to treat, on the basis of the control group, the observation group was treated by telmisartan, their blood pressure, blood-lipid and level of the glycosylated hemoglobin were observed and analysed after 12 weeks ......
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