N-CPAP治疗早产儿呼吸窘迫效果和围产因素关系的分析(1)
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[摘要] 目的：分析因呼吸窘迫接受鼻塞持续气道正压通气(N-CPAP)治疗的早产儿围产因素，了解其对治疗效果的影响。方法：将57例因呼吸窘迫接受N-CPAP治疗的早产儿，根据治疗结果分为N-CPAP成功组和N-CPAP失败组，比较两组患儿围产因素差异。结果：N-CPAP成功组和N-CPAP失败组在孕周、体重、性别和分娩方式差异无统计学意义；新生儿呼吸窘迫综合症(NRDS)早产儿中，N-CPAP治疗成功组和失败组比较，胸片分级构成比差异有统计学意义；羊水吸入综合征早产儿，其胸片分级构成比差异无统计学意义。结论：不能根据孕周、体重、性别和分娩方式判断N-CPAP治疗效果，N-CPAP对胸片分级RDS 3级以上NRDS早产儿呼吸窘迫治疗效果不佳。
[关键词] 早产儿；呼吸窘迫；围产因素；临床分析
[中图分类号] R725.6 [文献标识码] C[文章编号] 1674-4721(2011)06(b)-190-02
The analysis of therapy effect and perinatal factors used N-CPAP treat premature respiratory distress
WANG Xuesong
Department of Newborn, Yidou Hospital for Maternity and Child Care, Hubei Province, Yidou 443300
[Abstract] Objective: To analyze the respiratory distress accept N-CPAP therapy among perinatal factors, understanding the premature of treatment effect. Methods: 57 patients with respiratory distress accept N-CPAP therapy, all patients were divided into premature N-CPAP success group and N-failure group according to the treatment results, compared the differences among factors between the two groups. Results: N-CPAP successful group and N-CPAP failure group had no significant difference in the gestational of age, weight, gender and dilivery method, neonatal respiratory distress syndrome (NRDS), N-premature, successful treatment group and failure CPAP, chest radiograph grading constitute group compared was significant difference; than amniotic fluid, its chest radiograph inhaled syndrome grading constitute premature than no significant differences. Conclusion: We can not judge N-CPAP therapy effect according to the gestational of age, weight, gender and childbirth way. N-CPAP on chest radiograph RDS 3 class above NRDS grading premature respiratory distress treatment the effect are not very well.
[Key words] Premature; Respiratory distress; Perinatal factor; Clinical analysis
早产儿呼吸窘迫是临床常见症状，鼻塞持续气道正压通气(N-CPAP)对大部分早产儿呼吸窘迫有很好的效果，患儿症状减轻或消失[1]；但也有一部分患儿因为呼吸窘迫症状进展，N-CPAP治疗失败需要呼吸机治疗，早产儿围产因素对于N-CPAP治疗效果是否有影响的研究不多，了解这些情况有助于对呼吸支持方式的选择。
1 资料与方法
1.1 一般资料
选择2008年6月～2010年8月年在本科住院并接受N-CPAP治疗的呼吸窘迫早产儿57例 ......
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